Supplements, which were considered an alternative to promote various aspects of a healthy and balanced, have aroused growing distrust on the part of the medical community, due to the increase in reports of adverse effects.
Among a variety of products under study, the extract of Green Tea stands out as a focus of concern among experts.
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This tea is appreciated for its properties antioxidants, which can help prevent numerous diseases, and is therefore recommended for different health conditions.
Despite the similarity, tea is different from the extract derived from the plant in terms of concentration of catechins and caffeine, presenting significantly higher levels compared to a simple tea bag.
Although catechins are natural chemical compounds made up of plants, it is worth mentioning that caffeine, when accumulated in excess in the liver, can pose a risk.
Concerns about the possible adverse consequences of green tea extract have been documented in The Journal of Dietary Supplements. A recent study concluded that prolonged use of high doses of this product can cause liver damage.
Research has found that certain genetic variations make some people more susceptible to showing signs of liver stress after a year of ingesting green tea extract.
(Image: disclosure)
Participants received a daily dose of 843 milligrams of green tea's main antioxidant catechin, epigallocatechin gallate (EGCG).
The analysis revealed that early liver damage restrictions were more common in women with a specific genetic variation in the catechol-O-methyltransferase (COMT) gene.
The effects were still largely predicted by another genetic variation in the Uridine 5-diphospho-glucuronosyltransferases 1A4 (UGT1A4) gene.
In the case of participants with a high-risk UGT1A4 genotype, an enzyme that signals liver stress increased by almost 80% after nine months of taking the green tea supplement.
Despite these results, the researchers emphasize that it is still a challenge to predict who can safely extract the extract in high doses.
The conclusion of the analysis indicates that, although liver toxicity is associated with the ingestion of high doses of green tea extract, lower amounts and consumption of regular green tea do not appear to have the same scratchs.
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