A promising breakthrough was achieved by researchers at the Massachusetts Eye and Ear hospital, in the United States, when they tested a treatment experiment that demonstrated efficacy in reversing genetic hearing loss in the elderly.
Using AAV (adeno-associated virus) vectors in old mice, scientists modified a defective gene (TMPRSS3) that is responsible for hearing loss in humans. This discovery brings hope for the development of future treatments in humans.
see more
Gene therapy eye drops bring hope to millions of people…
Better Health in Two Days: The Surprising Effectiveness of End Workouts…
The results of this study were released on Friday, 26, in the scientific journal Molecular Therapy, providing further evidence on the effectiveness of this innovative approach in treating genetic hearing loss in the elderly.
It is estimated that by 2050, one in ten people will live with some form of hearing loss. Among the millions of cases of hearing loss worldwide, genetically based hearing loss is often the most challenging to treat.
There are four stages of hearing loss: mild, moderate, severe and profound. These categories reflect variations in a person's ability to hear, with the decibel being used as a measure of sound intensity. Each stage represents different degrees of difficulty in picking up sounds.
For example, normal hearing is capable of hearing sounds below 25 decibels, such as the singing of a bird, which can be around 10 decibels, or the noise of a wall clock hand, which is around 30 decibels.
After injecting VAA containing a functional version of the TMPRSS3 gene, the researchers witnessed remarkable hearing recovery.
In a statement, Zheng-Yi Chen, one of the researchers involved in the study, expressed that the results obtained indicate that the therapy Virus-based genetics, alone or combined with a cochlear implant, could be a viable option in treating hearing loss genetics.
According to the scientist, this study represents the first time that hearing has been recovered in elderly mice, which indicates the possibility of applying this method in older individuals. old.
Lover of movies and series and everything that involves cinema. An active curious on the networks, always connected to information about the web.
